Vitamins & Minerals
Adamco Products
Indications & Use:
For the supportive treatment of neuritis and non-inflammatory diseases of the nerves, e.g:
  •     Pain and/or paralysis in the facial nerves (trigeminal neuralgia, facial paresis)
  •     Ischialgia
  •     Optic neuritis
  •     Sciatica
  •     Pain in the area of the intercostals nerves, cervical vertebral column, shoulders and arms, as well as of the lumbar vertebral column
  •     States of irritation due to diseases of the vertebral column
Contraindications:
  • Adavit NeuroFort coated tablets must not be taken in known hypersensitivity to any of the drug ingredients.
  • Pregnancy and nursing period:
  • No adverse effects during pregnancy have so far been reported after intake of vitamins B1, B6 and B12, in the recommended dosage. No studies are available on possible accumulation of the vitamins in breast milk beyond the normal range.
  • In the individual case the doctor decides whether Adavit NeuroFort coated tablets should be taken during pregnancy or the nursing period.
  • Precautions:
  • You should inform your doctor immediately of any signs of side effects or in the case of pregnancy
  • Drug Interactions
  • If taken simultaneously with L-dopa (drug against Parkinson’s disease) Adavit NeuroFort coated tablets can reduce the dopa effect.
  • Proton pump inhibitors (Omeprazole, lansoprazol) and H2 receptor antagonists (Cimitidine, Famotidine, Ranitidine) can interfere with vitamin B12 absorption by slowing the release of gastric acid into the stomach.
  • Metformin might reduce the absorption of vitamin B12, and B1
  • Isoniaside, cycloserin, pyrazinamide and penicillamine may antagonize the effects of vitamin B6
  • Antacids  and Barbiturates may lower B1 levels in the body
  • Oral contraceptives may decrease levels of some B vitamins
  • Vitamin B1 may increase the effect of vasodilators in Diabetic patients
  • People receiving fluorouracil-containing chemotherapy regimens may be at risk for developing symptoms and signs of vitamin B1 deficiency.

Adverse reactions:
There have been very rare reports of hypersensitivity reactions (e.g. skin rashes, redding, vesicle formation) after administration of vitamin B1, but also of vitamin B12. 
Consult your doctor if the previous reactions happened.

Overdosage:
No overdosage symptoms are to be expected in the recommended dosage.

After prolonged intake of considerably higher doses the following complaints may occur:
  • Vitamin B6: Nerve lesions with sensorimotor disturbances, spasms and, in individual cases, changes in the blood count as well as inflammatory skin reactions after doses of more than 2 g daily have been described.
  • Vitamin B12: Allergic reactons, eczematous skin changes and a benign form of acne after high doses have been observed in rare cases.
  • If you have forgotten to take Adavit NeuroFort coated tablets, you must not make up for it by doubling the next dose, simply take the next dose at the usual time.

Dosage and Administration:
Generally: One coated tablet 3 times daily. The coated tablets should be taken whole with some liquid after meals.

Presentation:
Carton box contains 30 coated tablets in blister PVDC/AL