Adamco Products
Pharmacological Category:
Ischemic heart disease drug (vasodilator from the nitrates group).
Each tablet of Adanitra Mono 10mg contains: Isosorbide mononitrate 10mg.
The principal pharmacological action of isosorbide mononitrate is relaxation of vascular smooth muscle and consequent dilatation of peripheral arteries and veins, especially the latter.
Dilatation of the veins promotes reducing left ventricular end-diastolic pressure and pulmonary capillary wedge pressure (preload).
Arteriolar relaxation reduces systemic vascular resistance, systolic arterial pressure, and mean arterial pressure (afterload). Dilatation of the coronary arteries also occurs.
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