Why Vitamins are

Vitamin E , C ,A

Specific antioxidant treatment should be considered with other medications used to control hyperglycemia, hyperlipedimia, and hypertension for high-risk diabetic patients to protect their islets, reduce insulin resistance, and reduce the microvascular and macrovascular               complications of diabetes (25,41,42). Increasing the level of dietary fat-soluble antioxidant  vitamins in patients with hyperlipoproteinemia could conceivably reduce auto-oxidation in the chylomicrons or lipoprotein particle

Vitamin B complex

1- Homocysteine Metabolism : Hhcys is a risk factor for overall mortality in type 2 diabetic patients

Adequate levels of the vitamins B6, B12, and folate are necessary for normal homocysteine metabolism (11)

 

2- Peripheral neuropathy: Vitamin B12 has been used as a treatment for peripheral neuropathy in diabetes

Supplementation with vitamins B1, B2 and B6 to a group of people with diabetic          neuropathy led to significant improvement in only four weeks (49)

 

3- Glucose intolerance: Deficiency of vitamin B6 is associated with glucose intolerance (1) and the risk of deficiency is increased with age, use of medications and poor glycemic control.

 

 

 

NicotinAmide

Nicotinamide acts by protecting pancreatic ß-cells from autoimmune destruction

Nicotinamide may additionally act as a weak antioxidant of nitric oxide radicals (7,8).

Nicotinamide may help to preserve residual ß-cell function in people with type 1 or type 2 diabetes.

 

Biotin

Biotin is a B vitamin needed to process glucose (51), and may reduce pain from diabetic nerve damage (52). It is also involved in the synthesis and release of insulin

Vitamin C

Serum vitamin C concentrations have been reported to be low in diabetic patients (44) and closely associated with concomitant renal dysfunction and low-grade inflammation.

Epidemiologic studies showed an inverse relation between serum levels of vitamin C and blood pressure (46) and a reduced concentration of vitamin C in diabetic retinopathy (47

 

Chromium

 

1.       Chromium is required for the maintenance of normal glucose metabolism. It act by:

a)      enhancing or potentiating insulin’s actions (17),

b)      increasing the number of insulin receptors (16),

c)       increased binding of insulin to the insulin receptor, and

d)      increased activation of the insulin receptor in the presence of insulin (17).

2.       Chromium may also lower triglycerides (53).

3.       The typical amount of chromium used in research trials is 200mcg per day. Some doctors recommend up to 1000mcg per day for diabetics.

 

Zinc

People with type 2 diabetes have low zinc levels, caused by excess loss of zinc in their urine (58).

Zinc deficiency may impair immune function (55). Supplements have been showed to lower blood sugar levels in diabetics (56). Many      doctors recommend that people with type 2 diabetes supplement with moderate amounts of zinc (15–25 mg per day) as a way to correct for the deficit.


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